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FDAFDA · Food and drugs·Recall number Z-0188-2013

cobas 4800 BRAF V600 Mutation Test for In Vitro Diagnostic Use Roche Molecular Systems, Inc., Product Usage: The primary use of the cobas 4800 BRAF V600 Mutation Test is the detection of the BRAF V600 mutations in DNA extracted from formalin-fixed, paraffin-embedded human melanoma tissue. It is intended to be used as an aid in selecting melanoma patients whose tumors carry BRAF V600 mutations for treatment with Zelboraf (vemurafenib).

Published November 7, 2012 · Recall initiated: July 31, 2012

Status when published: Terminated — openFDA updates weekly, so this field may not reflect the current status. Always confirm with the official notice.

What's the hazard

It was identified that BRAF controls dispositioned as "Internal Use Only" were incorrectly packaged into cobas 4800 BRAF V600 Mutation Test CE-IVD kit lot R03607 and released for distribution. Two control batches manufactured during two process validation studies are involved: PV7711: BRAF Mutant (MUT) Control PV0853: BRAF Wild Type (WT) Control

What to do

Voluntary: Firm initiated · E-Mail

Recall details

Manufacturer
Roche Molecular Systems, Inc.
Distributor
Worldwide Distribution - Australia, Austria, Belgium, China, Hungary, Turkey and United Kingdom.
Lot
Material number 05985595190; Lot number R03607
Risk classification
Class III
Area (FDA)
device
Country
United States

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